- Incubation period 10 - 12 days
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Prodrome
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- lasts 2 - 4 days (range 1 - 7 days)
- Stepwise increase in fever to 103° - 105°F or higher
- Cough, coryza (runny nose), or conjunctivitis
- Koplik spots, a rash (enanthem) present on mucous membranes
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Rash |
- 2-4 days after prodrome, 14 days after exposure
- Persists 5-6 days
- Begins on face and head
- Maculipapular, becomes confluent
- Fades in order of appearance
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- Isolation of mealses virus from a clinical specimen (eg: urine, nasopharynx))
- Significant rise in measles IgG by any standard assay (eg: EIA, HA)
- Positive serologic test for measles IgM antibody
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